Diagnostic Value of SMARCE1 and CRISP3 Combined with Tumor Markers in Cervical Cancer

Background: To investigate the diagnostic value of SMARCE1, cysteine-rich secreted protein 3 (CRISP3) combined with tumor markers in diagnosis cervical cancer. Methods: A total 80 patients lesions who were diagnosed and treated our hospital from January 2020 to March 2022 selected divided into control group (chronic cervicitis, n = 30) observation (cervical cancer, 50). Immunohistochemistry was used detect expression levels SMARCE1 CRISP3 tissue two groups subjects, relationship between cancer clinicopathological data analyzed. In addition, serum marker subjects detected, The female sexual function index (FSFI) functional assessment therapy-general (FACT-G) score evaluate quality life. Results: positive rates significantly higher than those (p < 0.05). There no significant difference among age, lymph node metastasis (TNM) classification stage > 0.05), lower degree differentiation, rate proteins carcinoembryonic antigen (CEA), carbohydrate (CA) 125 CA153 results receiver operating characteristic (ROC) curve analysis showed that area under (AUC) values + markers, CRISP3, for 0.760, 0.851, 0.739, 0.810, 0.944, respectively. Conclusions: are expressed CEA, CA125, at high detection has clinical